Methods development for total organic carbon accountability

This report describes the efforts completed during the contract period beginning November 1, 1990 and ending April 30, 1991. Samples of product hygiene and potable water from WRT 3A were supplied by NASA/MSFC prior to contract award on July 24, 1990. Humidity condensate samples were supplied on August 3, 1990. During the course of this contract chemical analyses were performed on these samples to qualitatively determine specific components comprising, the measured organic carbon concentration. In addition, these samples and known standard solutions were used to identify and develop methodology useful to future comprehensive characterization of similar samples. Standard analyses including pH, conductivity, and total organic carbon (TOC) were conducted. Colorimetric and enzyme linked assays for total protein, bile acid, B-hydroxybutyric acid, methylene blue active substances (MBAS), urea nitrogen, ammonia, and glucose were also performed. Gas chromatographic procedures for non-volatile fatty acids and EPA priority pollutants were also performed. Liquid chromatography was used to screen for non-volatile, water soluble compounds not amenable to GC techniques. Methods development efforts were initiated to separate and quantitate certain chemical classes not classically analyzed in water and wastewater samples. These included carbohydrates, organic acids, and amino acids. Finally, efforts were initiated to identify useful concentration techniques to enhance detection limits and recovery of non-volatile, water soluble compounds

Controlled Lagrangians and Potential Shaping for Stabilization of Discrete Mechanical Systems

The method of controlled Lagrangians for discrete mechanical systems is extended to include potential shaping in order to achieve complete state-space asymptotic stabilization. New terms in the controlled shape equation that are necessary for matching in the discrete context are introduced. The theory is illustrated with the problem of stabilization of the cart-pendulum system on an incline. We also discuss digital and model predictive control.Comment: IEEE Conference on Decision and Control, 2006 6 pages, 4 figure

Controlled Lagrangians and Stabilization of the Discrete Cart-Pendulum System

Matching techniques are developed for discrete mechanical systems with symmetry. We describe new phenomena that arise in the controlled Lagrangian approach for mechanical systems in the discrete context. In particular, one needs to either make an appropriate selection of momentum levels or introduce a new parameter into the controlled Lagrangian to complete the matching procedure. We also discuss digital and model predictive control

Matching and stabilization of discrete mechanical systems

Controlled Lagrangian and matching techniques are developed for the stabilization of equilibria of discrete mechanical systems with symmetry as well as broken symmetry. Interesting new phenomena arise in the controlled Lagrangian approach in the discrete context that are not present in the continuous theory. Specifically, a nonconservative force that is necessary for matching in the discrete setting is introduced. The paper also discusses digital and model predictive controllers

Effect of microgravity on several visual functions during STS shuttle missions

Changes in the acuity of astronaut vision during flight are discussed. Parameters such as critical flicker vision, stereopsis to 10 seconds of arc, visual acuity in small steps to 20/7.7, cyclophoria, lateral and vertical phoria and retinal rivalry were tested using a visual function tester. Twenty-three Space Transportation System (STS) astronauts participated in the experiments. Their vision was assessed twice before launch and after landing, and three to four times while on-orbit and landing. No significant differences during space flight were observed for any of the visual parameters tested. In some cases, slight changes in acuity and stereopsis were observed with a subsequent return to normal vision after flight

Definition of a near real time microbiological monitor for space vehicles

Efforts to identify the ideal candidate to serve as the biological monitor on the space station Freedom are discussed. The literature review, the evaluation scheme, descriptions of candidate monitors, experimental studies, test beds, and culture techniques are discussed. Particular attention is given to descriptions of five candidate monitors or monitoring techniques: laser light scattering, primary fluorescence, secondary fluorescence, the volatile product detector, and the surface acoustic wave detector

Melvin universe as a limit of the C-metric

It is demonstrated that the Melvin universe representing the spacetime with a strong 'homogeneous' electric field can by obtained from the spacetime of two accelerated charged black holes by a suitable limiting procedure. The behavior of various invariantly defined geometrical quantities in this limit is also studied.Comment: 5 pages, no figures [v2: two references added

Retinal redox stress and ultrastructural remodeling in metabolic syndrome and diabetic retinopathy [abstract]

Diabetic retinopathy is the major cause of blindness in the United States in the age group from 20-74. There are four traditional metabolic pathways involved in the development of diabetic retinopathy: increased polyol pathway flux, increased advanced glycation end-product formation, activation of protein kinase C (PKC) isoforms, and increased hexosamine pathway flux. These pathways individually and synergistically contribute to redox stress resulting in retinal tissue injury culminating in microvascular retinal remodeling and diabetic retinopathy. We investigated the ultrastructural remodeling of the blood retinal barrier (BRB) in the choroid coat layer and plexiform layers in retinas of the young 9 week old Zucker rat model of obesity and insulin resistance and the 20 week old alloxan diabetic porcine model with JEM -1400 transmission electron microscopy. Previous studies indicated that pericyte loss and dysfunction are the earliest hallmarks of diabetic retinopathy

Radiationless Travelling Waves In Saturable Nonlinear Schr\"odinger Lattices

The longstanding problem of moving discrete solitary waves in nonlinear Schr{\"o}dinger lattices is revisited. The context is photorefractive crystal lattices with saturable nonlinearity whose grand-canonical energy barrier vanishes for isolated coupling strength values. {\em Genuinely localised travelling waves} are computed as a function of the system parameters {\it for the first time}. The relevant solutions exist only for finite velocities.Comment: 5 pages, 4 figure